Cardiac Extracellular Matrix | From Fundamental Science to Clinical Applications
₨ 1,000 – ₨ 1,940Price range: ₨ 1,000 through ₨ 1,940
Cardiac Extracellular Matrix: Fundamental Science to Clinical Applications provides a comprehensive guide to ECM biology, its role in cardiac structure and function, and translational applications in regenerative medicine and cardiovascular therapy.
The writing style balances scientific rigor with clinical relevance, making it suitable for both research-focused readers and practicing clinicians. It serves as a comprehensive reference for understanding the role of ECM in cardiovascular health and disease, as well as its potential in developing innovative cardiac therapies.
Overall, Cardiac Extracellular Matrix: Fundamental Science to Clinical Applications is an essential resource for anyone seeking to understand the critical role of ECM in the heart and its applications in regenerative medicine, tissue engineering, and clinical cardiovascular therapies.
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Cardiac Extracellular Matrix: Fundamental Science to Clinical Applications is an authoritative resource that bridges basic science, translational research, and clinical application in cardiac biology. The book focuses on the extracellular matrix (ECM), a key component in maintaining cardiac structure, function, and repair, offering insights for researchers, clinicians, and cardiovascular specialists.
The text begins with fundamental ECM biology, including composition, structure, and function of cardiac extracellular matrix proteins. Chapters cover collagen, elastin, glycoproteins, and proteoglycans, emphasizing their role in myocardial mechanics, cellular signaling, and tissue homeostasis. Understanding ECM biology is essential for comprehending both normal cardiac physiology and the pathological remodeling seen in heart disease.
Subsequent sections address ECM remodeling in disease states, including myocardial infarction, heart failure, hypertrophy, fibrosis, and cardiomyopathies. The mechanisms underlying pathological ECM changes are discussed, highlighting how these processes contribute to impaired cardiac function and progression of cardiovascular disease.
A major focus is on translational and clinical applications, particularly in regenerative cardiology and tissue engineering. The book explores ECM-based scaffolds, biomaterials, and hydrogels for myocardial repair, emphasizing strategies to promote cell engraftment, angiogenesis, and functional recovery. Stem cell therapies, exosome-mediated ECM modulation, and gene therapies are also discussed in the context of ECM interactions.
Key features include:
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Comprehensive coverage of cardiac ECM biology and pathology
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Mechanistic insights into ECM remodeling in heart disease
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Translational applications in tissue engineering, regenerative medicine, and therapeutic design
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Evidence-based discussion of preclinical studies and emerging clinical strategies
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Integration of molecular, cellular, and biomechanical perspectives
The text includes detailed figures, diagrams, and tables to clarify complex mechanisms, ECM structures, and clinical applications. Case studies and real-world examples illustrate how ECM-targeted therapies are being applied in cardiovascular research and practice.
Cardiac Extracellular Matrix is particularly valuable for:
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Cardiologists and cardiac surgeons interested in regenerative therapies
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Researchers in molecular cardiology, tissue engineering, and ECM biology
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Graduate students, postdoctoral fellows, and academics in cardiovascular science
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Clinicians exploring novel therapies for myocardial infarction, fibrosis, and heart failure
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Professionals involved in translational research and clinical trial design
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| Dimensions | 11 × 8.5 × 21 cm |
|---|---|
| Quality |
matt color fished ,black and white |
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