Cardiovascular Regenerative Medicine | Tissue Engineering and Clinical Applications

Cardiovascular Regenerative Medicine: Tissue Engineering and Clinical Applications is an authoritative and forward-looking resource that bridges basic science, engineering, and clinical cardiology. Designed for cardiologists, researchers, and healthcare professionals interested in regenerative therapies, this book offers an in-depth exploration of cutting-edge strategies for repairing damaged heart and vascular tissues.

The text begins with a foundational overview of cardiovascular pathophysiology, including mechanisms of myocardial injury, vascular disease, and heart failure. Understanding these disease processes provides the basis for targeted regenerative interventions and tissue repair strategies.

Subsequent chapters focus on tissue engineering and stem cell-based therapies, including the biology of stem cells, scaffold design, biomaterials, and cell delivery methods. The book explains how these technologies are applied to repair myocardial tissue, promote angiogenesis, and improve cardiac function in preclinical and clinical settings.

The book also examines gene therapy, exosomes, and biologics as emerging regenerative modalities. It explores mechanisms of action, therapeutic potential, and translational challenges, emphasizing evidence from experimental studies and clinical trials. Safety, ethical considerations, and regulatory aspects are also discussed, providing a balanced view of clinical application.

A major strength of the text is its focus on translational medicine and clinical applications. Topics include regenerative strategies for myocardial infarction, ischemic heart disease, heart failure, congenital heart defects, and peripheral vascular disease. Case studies, clinical trial data, and real-world examples illustrate the practical implementation of regenerative therapies.

Key features include:

• Comprehensive coverage of tissue engineering, stem cell therapy, and regenerative approaches

• Integration of basic science, engineering principles, and clinical applications

• Evidence-based discussion of preclinical and clinical studies

• Ethical, safety, and regulatory considerations for regenerative medicine

• Future perspectives on personalized and precision regenerative therapies

Illustrations, tables, and schematics are used extensively to clarify complex concepts, including scaffold design, cellular differentiation, and tissue regeneration mechanisms. Stepwise explanations of clinical protocols and therapeutic strategies enhance usability for researchers and clinicians alike.

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